Effects of continuous tracheal gas insufflation during pressure limited ventilation on pulmonary surfactant in rabbits with acute lung injury
G Zhu, W Zhang, Z Hua, Y Liang - Chinese medical journal, 2006 - journals.lww.com
Background Pulmonary surfactant dysfunction may contribute to the development of
ventilator induced lung injury (VILI). Tracheal gas insufflation (TGI) is a technique in which
fresh gas is introduced into the trachea and augment ventilation by reducing the dead space
of ventilatory system, reducing ventilatory pressures and tidal volume (VT) while maintaining
constant partial arterial CO 2 pressure (PaCO 2). We hypothesised that TGI limited peak
inspiratory pressure (PIP) and VT and would minimize conventional mechanical ventilation …
ventilator induced lung injury (VILI). Tracheal gas insufflation (TGI) is a technique in which
fresh gas is introduced into the trachea and augment ventilation by reducing the dead space
of ventilatory system, reducing ventilatory pressures and tidal volume (VT) while maintaining
constant partial arterial CO 2 pressure (PaCO 2). We hypothesised that TGI limited peak
inspiratory pressure (PIP) and VT and would minimize conventional mechanical ventilation …
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